A poster comparing the mapping of a Mendelian trait (Cystic Fibrosis and a complex trait (Type 2 Diabetes)

the teacher wanna a POSTER compare the mapping of Mendelian trait ( she said u choose which disease u want so i choose Cystic Fibrosis disease) and Complex trait ( which i choose Type 2 diabetes and i am not sure about it). she wants some figures explain the gene locus, mapping, tests done on it before, and therapy. I attach some important instructions from the teacher. She draw an example as Huntingin disease and Autism. if u have an easier examples about Mendelian and complex diseases tell me please.
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Molecular Genetics Assessment Assignment
Students in BMS524 will create a poster comparing the mapping of a Mendelian trait and a complex
trait. Pick a human gene or trait from Online Mendelian Inheritance in Man (OMIM)
(http://www.ncbi.nlm.nih.gov/omim) and a complex trait (cancer, autism, Alzheimer’s disease). Outline
sources of material documenting how each trait is genetically mapped. Include the following:
a)
b)
c)
d)
e)
f)
g)
h)
Genotype and phenotypes.
Variation
Gene regulation
Developmental effects
Population studies
Application such as testing or therapy
Environmental links: does the gene have ecological significance?
Bibliography of key resources used
The poster will have a title, abstract, results, conclusions and key citations.
Rubric for evaluation:
Objective
To demonstrate
content
knowledge
Supports scientific
inquiry
Integration and
organization of
content
Use of resources
novice
Project failed to
demonstrate an
understanding of
mapping
techniques for
simple and
complex traits
Project did not
illustrate
techniques used
to map genes
emergent
Project
demonstrated a
limited
understanding of
gene mapping for
simple and
complex traits
Project illustrated
some techniques
used for gene
mapping
proficient
Project
demonstrate an
understanding of
gene mapping for
simple and
complex traits
advanced
Project
demonstrated
mastery of gene
mapping for
simple and
complex traits
Project accurately
demonstrated
how techniques
are used in gene
mapping
Project failed to
show contrast in
simple and
complex gene
mapping
Project did not
use resources
effectively
Project showed
some aspects of
contrast in simple
and complex gene
mapping
Project drew
upon some course
related resources
Project
demonstrated
contrast in simple
and complex gene
mapping
Project
incorporated
course resources
and additional
materials
Project
demonstrated
mastery of
scientific methods
used in gene
mapping
Project showed
mastery of
contrast and
comparison of
gene mapping
Project critically
analyzed all
resources,
incorporated
them into design
and conclusions

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